CAP TODAY Pathology/Laboratory Medicine/Laboratory Management
New England Biolabs has released WarmStart RTx Reverse Transcriptase, a novel, thermostable reverse transcriptase, specifically designed for nucleic acid detection.
“WarmStart RTx is an in silico–engineered thermostable reverse transcriptase, designed by our researchers for speed, sensitivity, and inhibitor resistance in reverse transcription loop-mediated isothermal amplification (RT-LAMP), RT-PCR, and other applications where the detection of low quantities of target RNA from complex sample matrices is critical,” Sir Richard Roberts, chief scientific officer, said in a statement.
WarmStart RTx is reversibly inhibited at room temperature and is activated when warmed above 40°C, enabling researchers to set up their reactions at room temperature with no background reverse transcriptase activity. Maximum activity is reached at 55°C, enabling high-temperature cDNA synthesis. This results in more consistent target detection across different RNA targets.
New England Biolabs, 978-927-5054