Tag Archives: Bruker—

July 2023—Bruker Corp. launched its TimsTOF Ultra mass spectrometer at the American Society for Mass Spectrometry annual conference, June 4–8, in Houston, Tex. TimsTOF Ultra can identify, with 125 pg of material, more than 5,500 protein groups in 22 minutes via a collision cross section–enabled TIMScore and TIMS DIA-NN 4D-Proteomics or Spectronaut 18 software. Its new Captive­Spray Ultra ion source with vortex flow enhances ion formation across nanoflow liquid chromatography gradients. The platform has a parallel accumulation–serial fragmentation (PASEF) scan speed of up to 300 Hz for tandem mass spectrometry.

August 2022—Bruker Corp. has launched PhenoRisk PACS RuO, a research use only nuclear magnetic resonance test for molecular phenomics research on blood samples of patients with post-acute COVID syndrome (PACS), or long COVID. The test uses a multiplexed combination of biomarkers and is for research on early-stage risk factors on longitudinal recovery monitoring and on potential secondary organ damage in cardiovascular disease, type 2 diabetes, kidney dysfunction, and inflammation. It runs on the Avance IVDr NMR spectroscopy system, which produces results in 20 minutes.

August 2021—Bruker launched, at the 31st European Congress of Clinical Microbiology and Infectious Diseases, products and methods for its MALDI Biotyper platform.

July 12, 2021—Bruker launched, at the 31st European Congress of Clinical Microbiology and Infectious Diseases products, and methods for its MALDI Biotyper platform.

September 2020—Bruker announced an advance in matrix-assisted laser desorption ionization with the launch of its MALDI-2 post-ionization (PI) source, now available as an option on the TimsTOF Flex ESI/MALDI mass spectrometer. The MALDI-2 technology can offer one or two orders of magnitude higher sensitivity for many small molecules and lipids, Bruker said. MALDI-2 increases the applications range of MALDI mass spectrometry and imaging even further. Bruker launched additional TIMS/PASEF-enabled 4D proteomics methods that leverage the large-scale, real-time availability of accurate collision cross sections (CCS) for thousands of measured peptides per 4D nanoLC-CCS-MS/MS run.

Bruker has announced what it says is a major expansion of its Mycobacteria Library for research use only on the MALDI Biotyper microbial mass spectrometry system.

August 2014—MALDI Biotyper systems can be configured for further functionality by adding new or expanded research-use only software modules or hardware accessories.

The MBT Explorer module provides multiple bioinformatics approaches for spectra comparison, statistical data interpretation, and the generation of customer-specific reference library entries (main spectra) of strains of special interest. Such sub-libraries can be exported and re-imported in networks of collaborating labs.

BD Diagnostics in April announced an international distributor agreement with Bruker Daltonics to sell and provide frontline technical support for the co-labeled BD Bruker MALDI Biotyper system. The system, combined with automated antimicrobial susceptibility testing on the BD Phoenix microbiology system and BD EpiCenter microbiology data management system, will facilitate a fully integrated, optimized approach for laboratory workflow.