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Stable-labeled internal standards, 9/15

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Sigma-Aldrich’s Cerilliant brand has introduced five stable-labeled internal standards of the antifungal agents fluconazole, itraconazole, ketoconazole, posaconazole, and voriconazole at 1.0 mg/mL concentrations.

The reference materials offer clinical and diagnostic testing labs, hospitals, and bioanalytical/pharmacokinetics and drug metabolism labs a full selection of internal standards for quantitation of common antifungal drugs in serum or plasma by mass spectrometry–based analytical methods.

The deuterium or 13C substitutions of each internal standard were chosen to conserve a minimum (M+3) separation from the unlabeled drug in the major ion fragments used in liquid chromatography–mass spectrometry/MS antifungal therapeutic drug monitoring applications and metabolism studies.

Cerilliant certified reference solutions are manufactured and certified to industry standards, including ISO Guide 34, ISO/IEC 17025, and ISO 13485, and are compliant with ISO 15194.

Cerilliant, 512-238-9974

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