Tag Archives: Bio SB

November 2023—Bio SB has launched a fully automated immunohistochemistry platform for deparaffinization and antigen retrieval and staining. Applications include immunohistochemistry, Mohs IHC, immunocytochemistry, and immunofluorescence of formalin-fixed, paraffin-embedded tissue, frozen tissue, and cell specimens.

Oct. 9, 2023—Bio SB has launched a fully automated immunohistochemistry platform for deparaffinization and antigen retrieval and staining.

April 2021—Bio SB has developed a new panel of SARS-CoV-2 antibodies to identify the COVID-19 virus, its receptors, and its cytokines by immunohistochemistry and immunofluorescence on formalin-fixed, paraffin-embedded biopsies. The antibodies identify ACE2, CD147, and TMPRSS2 receptors and include markers for immune response factors and vascular cells, with the intention to assess the pathological damage caused by COVID-19, cytokine storm syndrome, and coagulopathy, using single and multiplex IHC and immunofluorescence on FFPE tissues.

March 19, 2021—Bio SB has developed a new panel of SARS-CoV-2 antibodies to identify the COVID-19 virus, its receptors, and cytokines by immunohistochemistry and immunofluorescence on formalin-fixed, paraffin-embedded biopsies.

October 2020—Bio SB launched its Fast Mohs PolyDetector Plus Detection System, a highly sensitive nonbiotin monovalent Fab micropolymer IHC detection system for the detection of IVD antibodies for melanoma, basal cell carcinoma, and squamous cell carcinoma. It is intended for the detection of difficult nuclear targets such as androgen receptor, Ki-67, p40, p63, and SOX10.

July 29, 2020—Bio SB launched its Fast Mohs PolyDetector Plus Detection System, a highly sensitive nonbiotin monovalent Fab micropolymer immunohistochemistry detection system

November 2019—Bio SB has introduced its TintoDetector Mini Immuno staining system for immunohistochemical, immunocytochemistry, and immunofluorescence protocols in a semiautomated, open platform.

May 2019—Bio SB announced its line of Fast Mohs IHC antibodies and detection systems for immunohistochemical cancer detection on frozen tissue after Mohs surgery.

April 2017—Bio SB announced it now offers 25 monoclonal antibodies for IVD applications. Among the new products is a line of reagents for mesothelioma diagnosis, including BAP1, mesothelial cell HBME 1, and caveolin 1.

  May 2016—Bio SB is offering 50 new antibodies for in vitro diagnostic applications. This generation of antibodies offers higher affinity, sensitivity, and specificity when compared with the previous generation of mouse monoclonal and polyclonal antibodies traditionally used in diagnostic immunohistochemistry applications. “Our new RBT and EP clones of rabbit monoclonal antibodies are unique reagents for cancer research and diagnostics,” ...

January 2016—Bio SB introduced Helicobacter Pylori, MMab, Clone: BSB-37, a new line of mouse monoclonal antibodies for IHC with extensive protein immunogenicity analysis of targeted epitopes, high sensitivity specificity, and low background noise.

November 2015—Bio SB PolyDetector Systems are highly sensitive micropolymeric detection systems that allow for the demonstration of antigens in formalin-fixed, paraffin-embedded tissues, cryostat sections, blood smears, cytosmears, and cell preparations.

Bio SB announced a new line of rabbit monoclonal antibodies, SOX-10–RMab, for immunohistochemistry with extensive protein immunogenicity analysis of targeted epitopes, high sensitivity specificity, and low background noise.

July 2015—Bio SB announced a line of rabbit monoclonal antibodies, PD-L1/CD274, for immunohistochemistry with extensive protein immunogenicity analysis of targeted epitopes, high sensitivity specificity, and low background noise.

March 2014—Bio SB launched the Normal Human Tissue Micro Array and the Infectious Disease Cell Line Micro Array. The NH-TMA arrays are available in 11- or 23-core configurations, allowing testing of multiple tissues on one slide, and are validated for use with more than 100 antibodies in immunohistochemistry.

December 2013—Bio SB, a molecular pathology company based in Santa Barbara, Calif., announced the launch of its Bcl-6 rabbit monoclonal antibody for in vitro diagnostic use. Bcl-6 is a transcriptional regulator gene that codes for a 706-amino-acid nuclear zinc finger protein.

Bio SB, a molecular pathology company based in Santa Barbara, Calif., has announced that it will partner with Cancer Diagnostics Inc. to distribute the Bio SB line of IHC antibodies, chromogens, and ancillaries in the U.S. market.

Bio SB now offers HRP Green, a vibrant chromogen to help clinical and research laboratories detect IHC markers on paraffin-embedded tissues. HRP Green comes in a two-part buffer and chromogen format that is compatible with all Bio SB polymer and biotin HRP-based detection systems. HRP Green requires a five-minute incubation period, can be counterstained with Nuclear Fast Red or hematoxylin, and is xylene (PermaMounter) compatible.

Bio SB offers a portfolio of more than 130 rabbit monoclonal antibodies. “Rabbit monoclonal antibodies offer higher sensitivity and specificity when compared to mouse monoclonal antibodies traditionally used in laboratory applications,” Alfonso Heras, president and CEO of Bio SB, said in a statement. “Coupled with our new line of detection systems and chromogens, such as our PolyDetector HRP Plus, PolyDetector AP, and HRP Green, Bio SB can offer a large array of immunohistochemistry products to pathologists around the world.”

Bio SB, through its partnership with ZytoVision of Germany, can now distribute a complete line of CE-approved chromogenic in situ hybridization and fluorescent in situ hybridization probes targeted for use in lung carcinomas. The line of lung carcinoma CISH and FISH probes includes ZytoLight ALK/EML4 Tricheck triple-color probe (Z-2144-200), ZytoDot EGFR/CEN7 dual-color probe (C-3033-400), and many more.