March 2014—Agilent Technologies introduced SureFISH ALK, ROS1, and RET break-apart translocation probes, expanding its offering of oligonucleotide-based fluorescent in situ hybridization products. The probes are repeat-free, able to target specific sequences of interest, and use high-fidelity oligos designed in silico.
For ALK, ROS1, and RET probes, Agilent has fine-tuned the probe size and oligo density to give brighter, more balanced signals than BACs. For ALK and RET break-aparts, a unique micro-gap designed to minimize distance between child probes enables tight signal co-localization.
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