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Agilent Technologies, 4200 TapeStation (Molecular, 2018)

Agilent Technologies, 4200 TapeStation (Molecular, 2018)

Automated molecular platforms, October 2018

Contact Information

Agilent Technologies
Santa Clara, CA

Name of instrument 4200 TapeStation
Country where designed/Manufactured/Reagents manufactured Germany/Germany/Germany, U.S.
Instrument FDA cleared or approved/Platform no/analytical
First year sold in U.S./Sold internationally/Installed 2015/2015/2015
Dimensions in inches (H × W × D)/Footprint in square feet/Noise generated in dB 17.1 × 20 × 17.5/2.4/<70 dBA
Supplied with UPS/BTU yes/170 per hr.
Physical contamination control features lid and seal
List price/Price for sample extraction and amplification detection modules
Purchase options/Minimum test volume requirements straight purchase/≤2 µL DNA or RNA sample
Co. performs installation, operation, and performance qualifications/Electrical requirements no/100–240 V AZ, 50–60 Hz, 50 W
Labor and parts warranties/Advanced operator training 1–5 years/yes
Delivery time/Delivery charges/Installer/Time to install on site 4 weeks/destination included/Agilent/2 hrs.
Training location/No. of techs that can receive initial training/Length of training/Retraining at company facility on site/1–5/2–3 hrs./no
Test menu genomic DNA, D1000, HS D1000, D5000, HS D5000, RNA, HS RNA
No. of tests for which analyzer has FDA-cleared applications/CE mark none/all available tests
Tests available on instrument in U.S./Outside U.S. all tests/all tests
Tests not available in U.S. but submitted to FDA/Available in other countries only none/none
Research-use-only assays/Tests in development all tests/—
Open-channel capabilities/Start-up and preparation time no/5–30 min.
Model type of sample-handling system/Maximum sample load capacity 4200 TapeStation (G2991AA)/96
Minimum specimen volume/Sample volume flexibility/Other sample volumes available 1–2 µL DNA or RNA sample/no/no
Minimum dead volume/Pediatric sample volume/Primary tube sampling —/—/no
Sample tube sizes/Sample barcode reading/Autodiscrimination in 1D or 2D —/no/no
Sample barcode languages/Sample types available in open mode —/DNA and RNA samples
Clot detection/Open extraction platform/Sample types (open extraction) no/no/DNA and RNA samples
Amplification reagents or methods supported
No. of different assays onboard at once/Programmed or calibrated at once 1/7
Tests per container set/Multiple reagent configurations supported 1/yes
Reagent container placed directly on system/Onboard test auto inventory yes/yes
Determines reagent volume in container/Reagent barcode reading/Reagents barcoded yes/yes/yes
Monitors expiration date/Auto lot recognition or calibration yes/no
Auto detection of adequate reagent or specimen/Reagents available yes/liquid
Reagent reconstitution required/Chemical contamination control no/—
Onboard test auto inventory/Capable of inventory monitoring by barcode yes/no
System is open to homebrew/General-purpose reagents allowed no/no
Same capabilities when third-party reagent used/Lot sequestering available no/no
Closed-vial stability for amplification reagents/Extraction reagents 4 months/4 months
Storage temp. requirement for amplification reagents/Extraction reagents 36°–46°F/36°–46°F
Shipment temp. requirement for amplification reagents/Extraction reagents 36°–46°F/36°–46°F
Minimum/Maximum reagent shelf-life guarantee 4 months/4 months
Autocalibration or autocalibration alert/Multipoint calibration supported yes/no
Assay calibrations required by end user/Calibrants can be stored onboard no/no
Multiple calibrant lots stored for same assay/Required calibration frequency no/ladder for sizing and internal markers for the quantification are used in each run
Length of assay calibration/Typical calibration frequency 1 sample per consumable (Tape)/each run
Onboard real-time QC/Supports multiple QC lot numbers per assay no/no
Auto shutdown*/Instrument warm-up time/Onboard software reviews QC no/—/yes
Total number of controls per batch for 24 tests/48 tests/72 tests/96 tests 2/3/5/7
Walkaway capacity/Tech hands-on time (both for batch of 96 samples) yes/5–30 min.
Uses disposable pipette tips/Maximum number of pipette tips stored yes/112
Time between start and initial result/Instrument automatic shutdown 15 min./no
Startup programmable/Remote system monitoring/Waste required for disposables no/no/Labwaste
Windows technology/Mouse or touchscreen/Modular add-on capability yes/mouse/no
Service contracts available/Mean time between failures/To repair failures preventive maintenance and extended warranty/—/—
Turnaround time for problem solving by phone/Email/Field service M–F, 7 am–5 pm/M–F, 7 am–5 pm/M–F, 7 am–5 pm
No. of U.S. field reps/Service engineer on-site response time/Hours and days available >10/—/M–F, 7 am–5 pm
Guaranteed response time/Modem servicing avail./System diagnose own malfunctions no/no/yes
Order parts via modem/Onboard error codes/Maintenance training demo module no/yes/yes
Average maintenance time for lab personnel/Onboard maintenance records yearly: 0–5 min./yes
Preventive maintenance per year for sample extraction/Amplification detection
Downtime for preventive maintenance/Spare parts on site 4 hrs./no
Software and LIS interface:
• Patient demographics and insurance data available via rules-based architecture no
• Data retrieval or Internet connectivity no
• Online real-time help, QC, stats, and management reports/Evaluates results validity no/yes
• Priority processing no
• Supports accession No. redundancy/Specimen carrier and level identification no/no
• Unique barcode per container/Multistop routing (1 tube to many workstations) no/no
• Specimen scheduling/Routes test to workstation/Automatic reflex, repeat, dilutions no/no/no
• Sample storage and retrieval software supports CLSI standards no
• LIS(s) interfaced live with lab automation systems/How LIS(s) interfaced with LAS no/—
• QC results transferred automatically to LIS/Data-management capability no/no
• Interfaces operational in active user sites no
• Rules-based control subsystem/Process control via control subsystem no/no
• LIS operates simultaneously with assays running no
• Uses LOINC to transmit orders and results/Unidirectional interface capability no/no
• Results immediately transmitted to LIS/Interface available to auto specimen-handling system no/no
• Stores QC lot files/Worklist edit capability/Viewable PCR graphs no/no/no
• Can print, archive, transmit data yes
Distinguishing features (supplied by company) automated: unattended walkaway operation with fully automated sample processing for up to 96 samples; flexible: ready-to-use ScreenTape technology enables easy switching between DNA and RNA assays; fast: simplify your workflow without any system setup procedures and obtain reliable results in as few as 1–2 min.
*for calibration and controls
Note: a dash in lieu of an answer means company did not answer question or question is not applicable
All information is supplied by the companies listed. The tabulation does not represent an endorsement by the CAP.