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Mouse monoclonal antibodies, 1/16

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January 2016—Bio SB introduced Helicobacter Pylori, MMab, Clone: BSB-37, a new line of mouse monoclonal antibodies for IHC with extensive protein immunogenicity analysis of targeted epitopes, high sensitivity specificity, and low background noise.

Helicobacter pylori is a Gram-negative, microaerophilic bacterium found in the stomach and may be present in other parts of the body, such as the eye.
The strain of H. pylori to which a person is exposed may influence the risk of developing gastric cancer. Strains of H. pylori that produce high levels of two proteins, vacuolating toxin A (VacA) and the cytotoxin-associated gene A (CagA), appear to cause greater tissue damage than those that produce lower levels or that lack those genes completely. These proteins are directly toxic to cells lining the stomach and signal strongly to the immune system that an invasion is underway. This antibody reacts with Helicobacter pylori on the surface of epithelial cells of infected specimens.

Bio SB , 805-692-2768

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