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Antimicrobial testing standards, 8/17

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August 2017—The Clinical and Laboratory Standards Institute has published a revised edition of “M100: Performance Standards for Antimicrobial Susceptibility Testing, 27th ed.,” its annual supplement that provides revised breakpoints, new testing recommendations, and reporting changes needed to incorporate into routine practice.

The document includes revisions to results reporting definitions to harmonize with the CLSI library of susceptibility testing documents and to colistin minimal inhibitory concentration breakpoints for Pseudomonas aeruginosa. Telavancin disk diffusion breakpoints were deleted from multiple tables, and epidemiological cutoff values were added for azithromycin and N. gonorrhoeae; colistin; and Enterobacter aerogenes, Enterobacter cloacae, E. coli, Klebsiella pneumoniae, and Raoultella ornithinolytica. The mCIM was added for suspected carbapenemase production in Enterobacteriaceae. QC ranges were added and/or changed for drugs and organisms.

CLSI, 610-688-0100

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